Benzonitrile, 2-chloro-4,5-difluoro- - Names and Identifiers
Benzonitrile, 2-chloro-4,5-difluoro- - Physico-chemical Properties
Molecular Formula | C7H2ClF2N
|
Molar Mass | 173.55 |
Density | 1.43±0.1 g/cm3(Predicted) |
Melting Point | 33-36℃ |
Boling Point | 231.5±35.0 °C(Predicted) |
Flash Point | 93.8°C |
Vapor Presure | 0.0622mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.513 |
MDL | MFCD02871619 |
Benzonitrile, 2-chloro-4,5-difluoro- - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S39 - Wear eye / face protection.
|
UN IDs | 3276 |
Hazard Class | 6.1 |
Benzonitrile, 2-chloro-4,5-difluoro- - Introduction
2-Chloro-4, 5-difluorobenzonitrile is an organic compound with the chemical formula C6H2ClF2N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow crystal
-Melting point: 70-72°C
-Boiling point: 180°C
-Density: 1.54g/cm³
-Insoluble in water, soluble in organic solvents such as ethanol and dimethyl ether.
Use:
-2-Chloro-4, 5-difluorobenzonitrile is an important chemical intermediate, which has a wide range of applications in the pharmaceutical, pesticide and dye industries.
-It can be used to synthesize a variety of drugs and biologically active molecules.
-In the pesticide manufacturing process, it can be used as a raw material for pesticides and fungicides.
-It can also be used for dye synthesis.
Preparation Method:
2-Chloro-4, 5-difluorobenzonitrile can be synthesized by the following methods:
-Reaction of 2-fluorobenzonitrile with acetyl chloride under alkaline conditions.
-Fluorination reaction of 2-chlorofluorobenzene in the presence of hydrofluoric acid.
Safety Information:
-2-Chloro-4, 5-difluorobenzonitrile is irritating and direct contact with skin and eyes should be avoided.
-Wear appropriate protective measures such as gloves and goggles during use.
-Avoid inhaling its vapors and need to operate in a well-ventilated place.
-During storage and transportation, it should be kept in a dry, cool, ventilated place, away from fire and oxidizing agents.
-If swallowed or inhaled too much, seek medical attention immediately.
Last Update:2024-04-09 02:00:42